February 2, Pregnant women who take the pain killer ibuprofen in the first 24 weeks of their pregnancy may be reducing the store of eggs in the ovaries of their daughters. Researchers have found the first evidence in human ovarian tissue that exposure to ibuprofen during the crucial first three months of foetal development results in a "dramatic loss" of the germ cells that go into making the follicles from which female eggs develop. The germ cells either died or failed to grow and multiply at the usual rate. The authors of the study, which is published today Friday in Human Reproduction 1 , one of the world's leading reproductive medicine journals, say that their findings raise concerns about the long-term effects of ibuprofen on the future fertility of women exposed to the pain killer when in their mothers' wombs.
Ibuprofen in the first three months of pregnancy may harm future fertility of baby girls
Is it safe to take ibuprofen during pregnancy? | BabyCenter
Medically reviewed by Drugs. If you are pregnant, you should ONLY take medications under the direction of your doctor. If approved by your doctor, ibuprofen may be used in early pregnancy, but do not use this medicine during the later part last 3 months or last trimester of pregnancy. As a treatment for mild-to-moderate pain, acetaminophen Tylenol is considered the drug of choice in pregnant women.
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Women who take even a small dose of painkillers such as ibuprofen early in their pregnancy more than double their risk of suffering a miscarriage, research shows. The findings prompted medical experts to advise mothers-to-be to avoid taking the drug and instead to use paracetamol for pain relief. Taking any painkillers from the class of medicines known as non-steroidal anti-inflammatory drugs NSAIDs — such as ibuprofen, naproxen and Diclofenac — in the first 20 weeks after conception increases the risk of miscarriage by 2. The paper, published in the Canadian Medical Association Journal, found that pregnant women taking any type of NSAID, and any dose of one, ran that scale of extra risk of spontaneous abortion. Researchers examined 4, cases of miscarriage, of which 7.